產(chǎn)品詳情
簡(jiǎn)單介紹:
Protocadherin8(PCDH8)(MiddleRegion)Peptide
詳情介紹:
| Blocked Antibody | anti-Protocadherin 8 (PCDH8) (Middle Region) antibody (ABIN2782184) |
| Characteristics | This is a synthetic peptide designed for use in combination with anti-PCDH8 antibody (Catalog #: ARP45338_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. |
| Purification | Purified |
| Background |
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. PCDH8 is an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region.This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails. Alias Symbols: ARCADLIN, PAPC Protein Interaction Partner: PCDH8,UBQLN4 Protein Size: 973 |
| Molecular Weight | 101 kDa |
| Gene ID | 5100 |
| NCBI Accession | NM_032949, NP_116567 |
| UniProt | Q5TAN1 |
| Research Area | Signaling |
| Application Notes | Each Investigator should determine their own optimal working dilution for specific applications. |
| Restrictions | For Research Use only |
| Format | Lyophilized |
| Reconstitution | Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS. |
| Concentration | 1 mg/mL |
| Buffer | Final peptide concentration is 1 mg/mL in PBS. |
| Handling Advice | Avoid repeated freeze-thaw cycles. |
| Storage | -20 °C |
| Storage Comment | For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |