產(chǎn)品詳情
所在位置: 首頁> 產(chǎn)品目錄> 試劑>

  • 產(chǎn)品名稱：Dacogen

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：TargetMol
  • 產(chǎn)品文檔：
你添加了1件商品 查看購物車
簡單介紹：
Dacogen
詳情介紹：
Purpose Decitabine is indicated for treatment of patients with myelodysplastic syndrome (MDS). It is a chemical analogue of cytidine, a nucleoside present in DNA and RNA. Cells in the presence of Decitabine incorporate it into DNA during replication and RNA during transcription. The incorporation of Decitabine into DNA or RNA inhibits methyltransferase thereby causing demethylation in that sequence. This adversely affects the way that cell regulatory proteins are able to bind to the DNA/RNA substrate.
Characteristics Tradename: DAUNOXOME
Source of Compound: Streptomyces peucetius, FI-6339, NDC-0082-4155, RP-13057
Target: DNA Methyltransferase inhibitor
Receptor: DNA Methyltransferase
Status: USAN, INN, BAN, JAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 99.50?%
Formula C8H12N4O4
Solubility DMSO 45 mg/mL,Water 10 mg/mL
Molecular Weight 228.21 g/mol
CAS-No 2353-33-5
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months
Supplier Images
image for Dacogen (ABIN4874093) Dacogen