產(chǎn)品詳情
簡單介紹:
(S)-H-1152dihydrochloride
詳情介紹:
Purpose | A potent, specific ATP-competitive rho-kinase (ROCK) inhibitor |
Characteristics | H-1152 dihydrochloride is a potent, cell permeable, specific, ATP-competitive inhibitor of Rho-kinase (ROCK) (Ki = 1.6 nM). H-1152 poorly inhibits PKA, PKC, and myosin light chain kinase (Ki = 0.63, 9.27, and 10.1 μM, respectively). |
Purity | ≥ 98?% by HPLC |
Chemical Name | (S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride |
Formula | C??H??N?O?S.2HCl |
Permeability | Cell-permeable |
Solubility | DMSO (>15 mg/ml) |
Molecular Weight | 392.34 g/mol |
CAS-No | 451462-58-1 |
Restrictions | For Research Use only |
Handling Advice | Protect from air and moisture |
Storage | -20 °C |
Expiry Date | 36 months |