產(chǎn)品詳情
簡單介紹:
Motesanib
詳情介紹:
Characteristics | Cell-permeable. Motesanib, also known as AMG-706, is a multikinase inhibitor that selectively targets VEGF receptors, platelet-derived growth factor receptors (PDGFRs), and Kit receptors with IC50 values of 2 nM (VEGFR1), 3 nM (VEGFR2), 6 nM (VEGFR3), 84 nM (PDGFR), and 8 nM (Kit). It also potently inhibits angiogenesis and induces regression in tumor xenografts. |
Purity | ≥ 98?% by HPLC |
Chemical Name | AMG-706 |
Formula | C??H??N?O |
Permeability | Cell-permeable |
Molecular Weight | 373.45 g/mol |
CAS-No | 453562-69-1 |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from air and moisture |
Storage | -20 °C |
Expiry Date | 24 months |
Supplier Images |
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