產(chǎn)品詳情
簡單介紹:
AS601245
詳情介紹:
Characteristics |
Cell-permeable. AS601245 is a potent, ATP-competitive JNK inhibitor (hJNK1: IC50 = 150 nM, hJNK2: IC50 = 220 nM and hJNK3: IC50 = 70 nM). Displays anti-inflammatory properties and has been shown to reduce TNF-alpha plasma levels induced by LPS in mice. Synonyms: (Z)-2-(Benzo[d]thiazol-2(3H)-ylidene)-2-(2-((-(pyridine-3-yl)ethyl)amino)pyridine-4-yl)acetonitrile |
Purity | ≥ 95?% by HPLC |
Chemical Name | (Z)-2-(Benzo[d]thiazol-2(3H)-ylidene)-2-(2-((-(pyridine-3-yl)ethyl)amino)pyridine-4-yl)acetonitrile |
Formula | C??H??N?S |
Permeability | Cell-permeable |
Molecular Weight | 372.45 g/mol |
CAS-No | 345987-15-7 |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from light and mositure |
Storage | -20 °C |
Expiry Date | 24 months |
Supplier Images |
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