產(chǎn)品詳情

  • 產(chǎn)品名稱：Chidamide

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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Chidamide
詳情介紹：
Characteristics Cell-permeable. A new benzamide class of histone deacetylase (HDAC) inhibitor with marked anti-tumor activity. It increases histone H3 acetylation levels in LoVo and HT29 colon cancer cells at concentrations as low as 4 μM. Additionally, chidamide affects the activation of oncogenic signaling kinases by dose-dependently reducing phosphorylated Akt, mTOR, p70S6k, Raf, and Erk1/2 protein expression in colon cancer cells.
Purity ≥ 98?%
Chemical Name N-?(2-?amino-?5-?fluorophenyl)-?4-?[[[1-?oxo-?3-?(3-?pyridinyl)-?2-?propen-?1-?yl]amino]methyl]-?benzamide
Formula C??H??FN?O?
Permeability Cell-permeable
Molecular Weight 390.41 g/mol
CAS-No 743420-02-2
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and mositure
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for Chidamide (ABIN1685543) Chidamide