產(chǎn)品詳情

  • 產(chǎn)品名稱：(-)-Blebbistatin

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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(-)-Blebbistatin
詳情介紹：
Characteristics Cell-permeable. The active enantiomer of (±)-Blebbistatin (ABIN1685823). A selective inhibitor of non-muscle myosin II ATPases. It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50= 0.5-5.0 μM), while weakly inhibiting smooth muscle myosin (IC50= 80 μM). Through these effects, (-)-blebbistatin reversibly blocks apoptosis-related bleb formation, directed cell migration and cytokinesis in vertebrate cells.
Purity ≥ 98?% by HPLC
Chemical Name 1,?2,?3,?3a-?tetrahydro-?3aS-?hydroxy-?6-?methyl-?1-?phenyl-?4H-?Pyrrolo[2,?3-?b]quinolin-?4-?one; (S)-Blebbistatin
Formula C??H??N?O?
Permeability Cell-permeable
Molecular Weight 292.34 g/mol
CAS-No 856925-71-8
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 36 months
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