Characteristics
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An anti-allergy, anti-asthma and anti-diabetic agent. Improves obesity-related metabolic dysfunction in mouse models. Increases thermogenesis and weight loss, decreases steatosis and improves insulin sensitivity. Inhibits TANK-binding kinase 1 (TBK1) and IKKe (IC50=1.2 μM). Clinically useful in treatment of aphthus ulcers.
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