產(chǎn)品詳情

  • 產(chǎn)品名稱：RO-3306

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
RO-3306
詳情介紹：
Characteristics Cell-permeable. A selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A). Arrests cell cycle at G1, S, and G2/M and induces apoptosis in embryonic stem cells. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines, and suppresses phosphorylation of p53 at Ser315 and procaspase-8 at Ser387.
Synonyms: (5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one
Purity ≥ 95?% by NMR
Chemical Name (5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one
Formula C??H??N?OS?
Permeability Cell-permeable
Molecular Weight 351.45 g/mol
CAS-No 872573-93-8
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for RO-3306 (ABIN1303973) RO-3306