產(chǎn)品詳情
簡單介紹:
SANT-1
詳情介紹:
Characteristics | Cell-permeable. A potent inhibitor of Sonic hedgehog (Shh) signaling, high affinity antagonist of smoothened activity (kDa= 1.2 nM). Inhibits smoothened agonist effects with an IC50of 20 nM in Shh-LIGHT2 cells.SANT-1 inhibits both wild type and oncogenic Smo with equal potency. |
Purity | ≥ 98?% by HPLC |
Chemical Name | N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4- (phenylmethyl)-1-piperazinamine |
Formula | C??H??N? |
Permeability | Cell-permeable |
Molecular Weight | 373.49 g/mol |
CAS-No | 304909-07-7 |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from light and air |
Storage | -20 °C |
Expiry Date | 60 months |
Supplier Images |
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