產(chǎn)品詳情

  • 產(chǎn)品名稱：YM201636

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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YM201636
詳情介紹：
Characteristics Cell-permeable. YM-201636 is a selective inhibitor of phosphoinositide kinase (PIK) PIKfyve (IC50 = 33 nM). It inhibits p110alpha at higher concentration (IC50 = 3 μM). It reversibly impairs endosomal trafficking in NIH3T3 cells, mimicking the effect produced by depleting PIKfyve with siRNA.YM-201636 also blocks retroviral exit by budding from cells.
Synonyms: 6-Amino-N-(3-(4-(4-morpholinyl)pyrido[3,?≤2,?≤:4,5]furo[3,2-d]pyrimidin-2-yl)phenyl)-3-pyridinecarboxamide
Purity ≥ 98?% by NMR
Chemical Name 6-Amino-N-(3-(4-(4-morpholinyl)pyrido[3'2':4,5]furo[3,2-d]pyrimidin-2-yl)phenyl)-3-pyridine carboxamide
Formula C??H??N?O?
Permeability Cell-permeable
Molecular Weight 467.49 g/mol
CAS-No 371942-69-7
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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image for YM201636 (ABIN1303983) YM201636