產(chǎn)品詳情

  • 產(chǎn)品名稱：I-BET151

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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I-BET151
詳情介紹：
Characteristics A BET bromodomain inhibitor that interacts with BRD4 and BRD3 BET proteins and displaces them from chromatin, displays highefficacy against human and murine MLL-fusion leukemic cell lines, through the induction of early cell cycle arrest and apoptosis. The mode of action is, at least in part, due to suppressing the transcription of key genes (BCL2, C-MYC and CDK6) that are critical for MLL-fusion leukemia maintenance.
Purity ≥ 98?% by HPLC (≥ 99.5?% optical purity)
Chemical Name GSK1210151A
Formula C??H??N?O?
Permeability Cell-permeable
Molecular Weight 415.44 g/mol
CAS-No 1300031-49-5
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 24 months
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image for I-BET151 (ABIN1685469) I-BET151