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Characteristics
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A cell-permeable prolyl 4-hydroxylase (P4H) inhibitor, inhibits hypoxia-inducible factor alpha (HIF-alpha) prolyl hydroxylase (HIF-PH). Increases levels of HIF-1alpha, promotes cell survival under hypoxic conditions. DMOG posseses neuroprotective effect on NFG deprived cell cultures through preservation of glucose metabolism. DMOG also attenuates myocardial injury in a rabbit ischemia reperfusion model.
Synonyms: N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
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