產(chǎn)品詳情

  • 產(chǎn)品名稱：AS604850

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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AS604850
詳情介紹：
Characteristics Cell-permeable. A selective, ATP-competitive inhibitor of PI3K+ with IC50 values of 0.25, > 20, > 20, and 4.5 μM for the human recombinant γ, delta, beta, and alpha isoforms, respectively. AS 604850 inhibits MCP-1-mediated monocyte chemotaxis with an IC50 value of 21 μM and reduces RANTES-induced peritoneal neutrophil recruitment in a murine model of leukocyte chemotaxis with an ED50 value of 42.4 mg/kg.
Purity ≥ 98?% by HPLC
Chemical Name 5-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethylene)-thiazolidine-2,4-dione
Formula C??H?F?NO?S
Permeability Cell-permeable
Molecular Weight 285.22 g/mol
CAS-No 648449-76-7
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 36 months
Supplier Images
image for AS 604850 (ABIN1685701) AS 604850