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  • 產品名稱：DAPT

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  • 產品廠商：Biovision
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DAPT
詳情介紹：
Characteristics Cell permeable. A potentinhibitor of gamma-secretase (IC50 = 115 nM for total beta-amyloid, IC50 = 200 nM for beta-amyloid 1-42). It reduces Abeta levels in vivo in plasma and cerebrospinal fluid in young and aged Tg2576 mice. Antagonizes Notch signaling through inhibition of Notch processing. DAPT treatment can influence hematopoietic cell fate decisions and enhances neuronal differentiation in embryonic stem cell-derived embryoidbodies independent of sonic hedgehog (shh) signaling.
Purity ≥ 98?% by TLC
Chemical Name N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester
Formula C??H??F?N?O?
Permeability Cell-permeable
Molecular Weight 432.46 g/mol
CAS-No 208255-80-5
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for DAPT (ABIN629194) DAPT