產(chǎn)品詳情
  • 產(chǎn)品名稱:Crizotinib

  • 產(chǎn)品型號:
  • 產(chǎn)品廠商:Biovision
  • 產(chǎn)品文檔:
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Crizotinib
詳情介紹:
Characteristics A specific, ATP-competitive, small-molecule inhibitor of the receptor tyrosine kinases (RTKs) c-Met and anaplastic lymphoma kinase (ALK). Iinhibits tyrosine phosphorylation of activated ALK at nanomolar concentrations. Inhibits the growth and survival of cell lines dependent upon c-Met or ALK enzymatic activity.
Purity ≥ 98?% by HPLC
Chemical Name 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine
Formula C??H??Cl?FN?O
Permeability Cell-permeable
Molecular Weight 450.34 g/mol
CAS-No 877399-52-5
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months
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