產(chǎn)品詳情
簡單介紹:
BAY11-7082
詳情介紹:
Characteristics | Potential anti-inflammatory agent. Selectively and irreversibly inhibits NF-kappaB activation by blocking TNF-alpha-induced phosphorylation of IkappaB-alpha without affecting constitutive IkappaB-alpha phosphorylation. Inhibits the TNF-alpha-induced surface expression of adhesion molecules ICAM-1, VCAM-1, and E-selectin in human endothelial cells with IC50 values of 5-10 μM. |
Purity | ≥ 98?% |
Chemical Name | (E)-3-(4-Methylphenylsulfonyl)-2-propenenenitrile |
Formula | C??H?NO?S |
Permeability | Cell-permeable |
Molecular Weight | 207.25 g/mol |
CAS-No | 195462-67-7 |
Research Area | Kinases/Phosphatases |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from air and light |
Storage | 4 °C |
Expiry Date | 24 months |
Supplier Images |
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