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  • 產品名稱：GW2580

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  • 產品廠商：Biovision
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GW2580
詳情介紹：
Characteristics A small-molecule, ATP-competitive inhibitor of cFMS kinase, at 60 nM it inhibits human cFMS kinase completely in vitro and was inactive against 26 other kinases. GW2580 also inhibits lipopolysaccharide (LPS)-induced TNF production in mice, but not LPS-induced TNF production in freshly isolated human monocytes and mouse macrophages in vitro.
Purity ≥ 99?% by HPLC
Chemical Name 5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine
Formula C??H??N?O?
Permeability Cell-permeable
Molecular Weight 366.41 g/mol
CAS-No 870483-87-7
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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