產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：Niclosamide

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
Niclosamide
詳情介紹：
Characteristics A STAT3 signaling pathway inhibitor. Niclosamide potently inhibits the activation and transcriptional function of STAT3 and induces cell growth inhibition, apoptosis, and cell cycle arrest of cancer cells with constitutively active STAT3. Also reversibly inhibits mTORC1 signaling and stimulates autophagy in vitro, displays antineoplastic effects in acute myelogenous leukemia (AML) stem cells.
Purity ≥ 98?% by HPLC
Chemical Name 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
Formula C??H?Cl?N?O?
Permeability Cell-permeable
Molecular Weight 327.12 g/mol
CAS-No 50-65-7
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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