產(chǎn)品詳情

  • 產(chǎn)品名稱：Ro31-8220methanesulfonate

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  • 產(chǎn)品廠商：Biovision
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簡單介紹：
Ro31-8220methanesulfonate
詳情介紹：
Characteristics Cell-permeable. A potent bisindolylmaleimide inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-alpha, PKC-betaI, PKC-betaII, PKC-gamma, and PKC-epsilon, respectively). It inhibits protein kinase A (PKA) (IC50 = 0.9 μM) and calcium/calmodulin kinase II (IC50 = 17 μM) at much higher concentrations. Also inhibits glycogen synthase kinase-3 (GSK-3) (IC50 = 6.8 nM).
Purity ≥ 98?% by NMR
Chemical Name 2-{1-[3-(Amidinothio)propyl]-1H-indol-3-yl}-3-(1-methylindol-3-yl)maleimide methanesulfonate; Bisindolylmaleimide IX methanesulfonate; BIM IX
Formula C??H??N?O?S.CH?O?S
Permeability Cell-permeable
Molecular Weight 553.65 g/mol
CAS-No 138489-18-6
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 36 months
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