產(chǎn)品詳情

  • 產(chǎn)品名稱：Nodularin

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
Nodularin
詳情介紹：
Characteristics Nodularin is a hepatotoxic monocylic pentapeptide produced by cyanobacterium Nodularia spumigena. It is a potent inhibitor of protein phosphatase types 1 (PP1) and 2A (PP2A), exhibiting IC50 values of 1.8 and 0.026 nM, respectively. It inhibits PP2B only at higher concentrations (IC50 = 1.8 μM).
Synonyms: Cyclo[3S-amino-9S-methoxy-2S,6E,8S-trimethyl-10-phenyl-4,6- decadienoyl-D-gamma-glutamyl-(2Z)-2-(methylamino)-2-butenoyl-(3S)- 3-methyl-D-beta-aspartyl-L-arginyl]
Purity ≥ 95?%
Chemical Name Cyclo[3S-?amino-?9S-?methoxy-?2S,?6E,?8S-?trimethyl-?10-?phenyl-?4,?6-? decadienoyl-?D-?γ-?glutamyl-?(2Z)-?2-?(methylamino)-?2-?butenoyl-?(3S)-? 3-?methyl-?D-?β-?aspartyl-?L-?arginyl]
Formula C??H??N?O??
Permeability Cell-permeable
Molecular Weight 824.96 g/mol
CAS-No 118399-22-7
Restrictions For Research Use only
Format Liquid
Buffer Ethanol
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
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