產(chǎn)品詳情

  • 產(chǎn)品名稱：GDC-0941

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
GDC-0941
詳情介紹：
Characteristics GDC-0941 is a potent inhibitor of p110alpha and p110delta (IC50 = 3 nM). It selectively binds to PI3K isoforms in an ATP-competitive manner, inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway.
Purity ≥ 99?% by HPLC
Chemical Name 2-(1H-Indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)-thieno[3,2- d]pyrimidine
Formula C??H??N?O?S?
Permeability Cell-permeable
Molecular Weight 513.64 g/mol
CAS-No 957054-30-7
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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image for GDC-0941 (ABIN412227) GDC-0941