產(chǎn)品詳情

  • 產(chǎn)品名稱：FASInhibitor,C75

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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FASInhibitor,C75
詳情介紹：
Characteristics Inhibitor of fatty acid synthase (FAS) reducing food intake and body weight in mice. Exhibits irreversible slow-binding biphasic inactivation of FAS. Down regulates neuropeptide Y and Agouti-related protein expression. Has been proposed to activiate CPT-1 activity in liver and adipose tissue, leading to increased fatty acid oxidation and energy production. Shows significant in vivo antitumor activity in human breast cancer cells. Suppresses DNA replication and induces apoptosis. FAS inhibition by C75 leads to dramatic accumulation of the CDK inhibitor p27KIP1 from cytosol to cell nuclei.
Purity ≥ 98?%
Chemical Name 4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid
Formula C??H??O?
Permeability Cell-permeable
Molecular Weight 254.3 g/mol
CAS-No 191282-48-1
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light
Storage -20 °C
Expiry Date 24 months
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