產(chǎn)品詳情

  • 產(chǎn)品名稱：AGE-BSA

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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AGE-BSA
詳情介紹：
Characteristics The AGE modified BSA was produced by reacting BSA with glycolaldehyde under sterile conditions followed by extensive dialysis and purification steps. Fluorescence of AGEs was confirmed by fluorescence spectrophotometry with Ex./Em. = 370/440 nm. Glycated BSA shows a 7000 % increase in fluorescence in compared to control BSA.
Application Notes During extended storage, AGE-BSA may precipitate. In this case, sonication will be helpful to solubilize the precipitates.
Restrictions For Research Use only
Format Liquid
Concentration 10 mg/mL
Buffer PBS
Storage -20 °C
Expiry Date 12 months
Product cited in: Liu, Yang, Chen, Cai, Lin, He: "Impact of ER stress-regulated ATF4/p16 signaling on the premature senescence of renal tubular epithelial cells in diabetic nephropathy." in: American journal of physiology. Cell physiology, Vol. 308, Issue 8, pp. C621-30, 2015 (PubMed).

Cerezo, Remáková, Tom?ik, Gay, Neidhart, Lukanidin, Pavelka, Grigorian, Vencovsky, ?enolt: "The metastasis-associated protein S100A4 promotes the inflammatory response of mononuclear cells via the TLR4 signalling pathway in rheumatoid arthritis." in: Rheumatology (Oxford, England), Vol. 53, Issue 8, pp. 1520-6, 2014 (PubMed).

Lan, Wu, Huang, Wu, Chen: "High-glucose environment enhanced oxidative stress and increased interleukin-8 secretion from keratinocytes: new insights into impaired diabetic wound healing." in: Diabetes, Vol. 62, Issue 7, pp. 2530-8, 2013 (PubMed).

Friggeri, Banerjee, Biswas, de Freitas, Liu, Bierhaus, Abraham: "Participation of the receptor for advanced glycation end products in efferocytosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 11, pp. 6191-8, 2011 (PubMed).

Tadié, Bae, Banerjee, Zmijewski, Abraham: "Differential activation of RAGE by HMGB1 modulates neutrophil-associated NADPH oxidase activity and bacterial killing." in: American journal of physiology. Cell physiology, Vol. 302, Issue 1, pp. C249-56, 2011 (PubMed).

Espiritu, Huang, Zhao, Mazzone: "Hyperglycemia and advanced glycosylation end products suppress adipocyte apoE expression: implications for adipocyte triglyceride metabolism." in: American journal of physiology. Endocrinology and metabolism, Vol. 299, Issue 4, pp. E615-23, 2010 (PubMed).

Kikuchi, Imakiire, Hyodo, Kushiyama, Higashi, Hyodo, Suzuki, Miura: "Advanced glycation end-product induces fractalkine gene upregulation in normal rat glomeruli." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 20, Issue 12, pp. 2690-6, 2005 (PubMed).