Comment
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Synonyms: 9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one SMER-3 (Small molecule enhancer of rapamycin -3) is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo. Induces the expression of MET genes that results in cell cycle arrest and blockage of cell proliferation
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