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                            產(chǎn)品詳情
                        
    
                        
    
                            
    
                                
                            
    
                            
    
                                
                                
                            
    
                            

                            
    
    
    
    
    
        
    
    
    
            
    

                
    
                    
                    
      
                          
    • 產(chǎn)品名稱：PHT-427
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    • 產(chǎn)品型號(hào)：
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    • 產(chǎn)品廠商：Biovision
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    • 產(chǎn)品文檔：
                          
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            簡(jiǎn)單介紹：
        
    
        
    
            PHT-427
        
    
    
    

    
    
        
    
            詳情介紹：
        
    
        
    
            
    
                
    
                    
                        
                        
                    
                    
                                                                                                                                                        
    
                                                                                    
                                                Purpose
                                            
                                        
                                                                                    
                                            
                                                A potent Akt and PDPK1 (3-Phosphoinositide Dependent Protein Kinase 1) inhibitor.
                                                                                            
                                                                            
    
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
    
                                                                                    
                                                Characteristics
                                            
                                        
                                                                                    
                                            
                                                White to off-white solid 
     Molecular formular: C20H31N3O3S2
                                                                                                		
                                                                            
    
                                                                                                                                                                                                                                                            
    
                                                                                    
                                                Purity
                                            
                                        
                                                                                    
                                            
                                                ≥ 98?% by HPLC
                                                                                            
                                                                            
    
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
    
                                                                                    
                                                Chemical Name
                                            
                                        
                                                                                    
                                            
                                                4-Dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide
                                                                                            
                                                                            
    
                                                                                                                                                                
    
                                                                                    
                                                Formula
                                            
                                        
                                                                                    
                                            
                                                C??H??N?O?S?
                                                                                            
                                                                            
    
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
    
                                                                                    
                                                Permeability
                                            
                                        
                                                                                    
                                            
                                                Cell-permeable
                                                                                            
                                                                            
    
                                                                                                                                                                                                                                                                            
                        
                
    
            
    
                                                                        
    
                
    
                    
                        
                        
                    
                    
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        
    
                                                                                    
                                                Molecular Weight
                                            
                                        
                                                                                    
                                            
                                                409.61 g/mol
                                                                                            
                                                                            
    
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
    
                                                                                    
                                                CAS-No
                                            
                                        
                                                                                    
                                            
                                                1191951-57-1
                                                                                            
                                                                            
    
                                                                                                                                                                                                                                                                            
                        
                
    
            
    
                                                            
    
                
    
                    
                        
                        
                    
                    
                                                                                                                                                                                                                                                    
    
                                                                                    
                                                Comment
                                            
                                        
                                                                                    
                                            
                                                
    Synonyms: 
     4-Dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide
    A potent Akt and PDPK1 (3-Phosphoinositide Dependent Protein Kinase 1) inhibitor. PH 427 binds to the pleckstrin homology (PH) domain of Akt and PDPK1 signaling with significant in vivo antitumor activity and minimal toxicity
    
                                                                                                		
                                                                            
    
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
    
                                                                                    
                                                Restrictions
                                            
                                        
                                                                                    
                                            
                                                For Research Use only
                                                                                            
                                                                            
    
                                                                                    
                        
                
    
            
    
                                                                                                
    
                
    
                    
                        
                        
                    
                    
                                                                                                                                                        
    
                                                                                    
                                                Format
                                            
                                        
                                                                                    
                                            
                                                Solid
                                                                                            
                                                                            
    
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
    
                                                                                    
                                                Handling Advice
                                            
                                        
                                                                                    
                                            
                                                Protect from air and light
                                                                                            
                                                                            
    
                                                                                                                                                                
    
                                                                                    
                                                Storage
                                            
                                        
                                                                                    
                                            
                                                -20 °C
                                                                                            
                                                                            
    
                                                                                                                                                                                                                                                            
    
                                                                                    
                                                Expiry Date
                                            
                                        
                                                                                    
                                            
                                                24 months
                                                                                            
                                                                            
    
                                                                                    
                        
                
    
            
    
                                                            
    
                
    
                    
                        
                        
                    
                    
                                                                                                                                                        
    
                                                                                    
                                                Supplier Images
                                            
                                        
                                                                                    
                                                
    
                    
    
            
    
                
                                             image for PHT-427 (ABIN1889120)
                        
                                    

                                    
                        PHT-427