產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：Ingenol

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
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簡(jiǎn)單介紹：
Ingenol
詳情介紹：
Purpose A diterpenoid related to phorbol that acts as a weak protein kinase C (PKC) activator
Characteristics Pale yellow solid
Molecular formular: C20H28O5
Purity ≥ 98?% by HPLC
Chemical Name (1aR,?2S,?5R,?5aR,?6S,?8aS,?9R,?10aR)-?1a,?2,?5,?5a,?6,?9,?10,?10a-?octahydro-?5,?5a,?6-?trihydroxy-?4-?(hydroxymethyl)-?1,?1,?7,?9-?tetramethyl-?1H-?2,?8a-?methanocyclopenta[a]cyclopropa[e]cyclodecen-?11-?one
Formula C20H28O5
Permeability Cell-permeable
Molecular Weight 348.44 g/mol
CAS-No 30220-46-3
Comment

Synonyms:
(1aR,2S,5R,5aR,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one
Ingenol is a diterpenoid related to phorbol that acts as a weak protein kinase C (PKC) activator that displays a Ki value of 30 M and an ED value of 27 M in vitro. Most ingenol esters are tumor-promoting. However, ingenol mebutate possesses anti-tumor activity when used topically for actinic keratosis
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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image for Ingenol (ABIN1889016) Ingenol