產(chǎn)品詳情
簡單介紹:
BEZ235(NVP-BEZ235)
詳情介紹:
Characteristics | Orally active PI-3 kinase inhibitor, Dual PI3K/mTOR inhibition, BEZ235 showed high target specificity and demonstrated anti-proliferative activity against tumor cell lines in animal models of cancer. |
Purity | ≥ 99?% by HPLC |
Chemical Name | NVP-BEZ235 |
Formula | C??H??N?O |
Permeability | Cell-permeable |
Molecular Weight | 469.55 g/mol |
CAS-No | 915019-65-7 |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from air and moisture |
Storage | -20 °C |
Expiry Date | 24 months |
Supplier Images |
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Product cited in: |
Berdichevsky, Dryer, Saponjian, Mahoney, Pimentel, Lucini, Usenovic, Staley: "PI3K-Akt signaling activates mTOR-mediated epileptogenesis in organotypic hippocampal culture model of post-traumatic epilepsy." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 21, pp. 9056-67, 2013 (PubMed).
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