產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：μ-ConotoxinPIIIA

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Smartox-Biotech
  • 產(chǎn)品文檔：
你添加了1件商品 查看購(gòu)物車(chē)
簡(jiǎn)單介紹：
μ-ConotoxinPIIIA
詳情介紹：
Purpose μ-Conotoxin PIIIA blocks Nav1.2 and Nav1.7 channels
Sequence H-pGlu-Arg-Leu-Cys4-Cys5-Gly-Phe-Hyp-Lys-Ser-Cys11-Arg-Ser-Arg-Gln-Cys16-Lys-Hyp-His-Arg-Cys21-Cys22-NH2(Disulfide bonds between Cys4-Cys16, Cys5-Cys21 and Cys11-Cys22)
Background μ-Conotoxin PIIIA has been isolated from the venom of the cone Conus purpurascens. μ-Conotoxins bind and block site 1 of voltage-gated sodium channels. This toxin blocks the neuronal sodium channels Nav1.2 (SCN2A) and Nav1.7 (SCN9A). The peptide causes flaccid paralysis in both mice and fish.
Molecular Weight 2604.1 Da
Restrictions For Research Use only