產品詳情

  • 產品名稱：MutSHomolog2,ColonCancer,NonpolyposisType1(E.Coli)(MSH2)(N-Term)Peptide

  • 產品型號：
  • 產品廠商：半導體
  • 產品文檔：
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簡單介紹：
MutSHomolog2,ColonCancer,NonpolyposisType1(E.Coli)(MSH2)(N-Term)Peptide
詳情介紹：
Blocked Antibody anti-MSH2 (N-Term) antibody (ABIN2776761)
Characteristics This is a synthetic peptide designed for use in combination with anti-MSH2 antibody (Catalog #: ARP41351_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alias Symbols: COCA1, FCC1, HNPCC, HNPCC1, LCFS2

Protein Interaction Partner: E2F1,E2F1,E2F3,E2F4,BRCA1,EXO1,EXO1,MAX,MSH3,MSH6,MSH6,ATR,ATRIP,BARD1,CHEK2,CREBBP,EXO1,MAX,MSH3,MSH6,PCNA,SMC1A,AIRE,ATM,ATR,ATRIP,BARD1,BLM,BRCA1,BTBD12,CHEK1,CHEK2,EXO1,MAX,MLH1,MRE11A,MSH2,MSH3,MSH6,MYC,NBN,OTUB1,PCNA,PMS2,PTP4A3,RAD50,RFC1

Protein Size: 934
Molecular Weight 105 kDa
Gene ID 4436
NCBI Accession NM_000251, NP_000242
UniProt P43246
Research Area DNA/RNA, Cancer
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.