產(chǎn)品詳情

  • 產(chǎn)品名稱：CEP-32496

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：TargetMol
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
CEP-32496
詳情介紹：
Purpose CEP-32496 is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFRβ and VEGFR2, respectively, insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2. Phase 1/2.
Characteristics Target: Raf inhibitor
Receptor: B-Raf/C-Raf,c-Kit,LCK,PDGFR,RET,Abl
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98?%
Formula C24H22F3N5O5
Solubility 10 mM in DMSO
Molecular Weight 517.46 g/mol
CAS-No 1188910-76-0
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months