產(chǎn)品詳情

  • 產(chǎn)品名稱：LFM-A13

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
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LFM-A13
詳情介紹：
Characteristics FM-A13 is a selective inhibitor of Bruton's tyrosine kinase (BTK) IC50's = 2.5 μM (recombinant BTK) and 17.2 μM (human BTK). It has also been shown to inhibit Polo-like kinase (PLK) (IC50= 61 μM for human PLK3). It displays no activity (concentrations up to 278 μM) at JAK1, JAK3, HCK, EGFRK and IRK2 or CDK1-3, CHK1, IKK, MAPK1, SAPK2a and ten tyrosine kinases.
Purity ≥ 98?% by TLC
Chemical Name (2Z) -2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide
Formula C??H?Br2N?O?
Permeability Cell-permeable
Molecular Weight 360 g/mol
CAS-No 244240-24-2
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 36 months
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