產(chǎn)品詳情
簡單介紹:
Itraconazole
詳情介紹:
Characteristics | A synthetic broad-spectrum triazole antifungal agent with the mode of action being through Inhibition of cytochrome P450 dependent enzymes including 14alpha-demethylase. Recently, it has been shown that Itraconazole inhibits Hedgehog (Hh) signaling pathway activity (IC50 = 0.8 μM) as well as blocks the VEGFR2 glycosylation, trafficking, and signaling in endothelial cells. |
Purity | ≥ 97?% |
Chemical Name | (2R,4S)-rel-1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one; Oriconazole, R51211, Sporanox |
Formula | C??H??Cl?N?O? |
Permeability | Not-permeable |
Molecular Weight | 705.63 g/mol |
CAS-No | 84625-61-6 |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from light and air |
Storage | -20 °C |
Expiry Date | 60 months |
Supplier Images |
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