產(chǎn)品詳情

  • 產(chǎn)品名稱：GANT61

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
GANT61
詳情介紹：
Characteristics Cell-permeable. A Hedgehog (Hh) signaling pathway antagonist. Inhibits Hh signaling downstream of Smo and Sufu at the level of Gli (IC50 = 5 μM). GANT61 has also been shown to inhibit the in vitro proliferation of PANC1 and 22Rv1 cells which have elevated GLi11 levels and prevent the development of 22Rv1 tumors in mice.
Purity ≥ 98?% by HPLC
Chemical Name 2,?2'-?[[dihydro-?2-?(4-?pyridinyl)-?1,?3(2H,?4H)-?pyrimidinediyl]bis(methylene)]bis(N,?N-?dimethyl-?benzenamine); NSC 136476
Formula C??H??N?
Permeability Cell-permeable
Molecular Weight 429.6 g/mol
CAS-No 500579-04-4
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months
Supplier Images
image for GANT61 (ABIN629266) GANT61