產(chǎn)品詳情
簡(jiǎn)單介紹:
EZSolution?Torin1
詳情介紹:
Brand | EZSolution? |
Characteristics | A potent, selective and ATP-competitive mTOR inhibitor, with IC50values of 2 and 10 nM for mTORC1 and mTORC2 respectively, Torin1 displays 1000-fold selectivity for mTOR over PI3K (EC50 = 1800 nM) and exhibits 100-fold binding selectivity relative to 450 other protein kinases. |
Purity | ≥ 98?% by HPLC |
Chemical Name | 1-[4-[4-(1-Oxopropyl)-1-piperazinyl-]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-benz-o[h]-1,6-naphthyridin-2(1H)-one |
Formula | C??H??F?N?O? |
Permeability | Cell-permeable |
Molecular Weight | 607.62 g/mol |
CAS-No | 1222998-36-8 |
Restrictions | For Research Use only |
Format | Liquid |
Buffer | A 10 mM solution in DMSO |
Handling Advice | Protect from light and moisture |
Storage | -20 °C |
Expiry Date | 12 months |
Supplier Images |
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