產(chǎn)品詳情

  • 產(chǎn)品名稱：GDC-0449

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
GDC-0449
詳情介紹：
Characteristics A potent inhibitor of Smoothened (SMO), a key mediator of Hedgehog (Hh) signaling pathway. Inhibition of SMO renders the transcription factor GLI inactive, thus preventing the expression of genes that mediate the role of Hh on tumor growth.
Purity ≥ 98?% by HPLC
Chemical Name 2-Chloro-N-(4-chloro-3-(pyridine-2-yl)phenyl)-4-(methylsulfonyl)benzamide; HhAntag691
Formula C??H??Cl?N?O?S
Permeability Cell-permeable
Molecular Weight 421.3 g/mol
CAS-No 879085-55-9
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months
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image for GDC-0449 (ABIN629262) GDC-0449