產(chǎn)品詳情
簡單介紹:
GemcitabineHydrochloride
詳情介紹:
Characteristics | A nucleoside analog of deoxycytidine used in chemotherapy to treat various types of cancer. Gemcitabine is converted intracellularly to the active metabolites difluorodeoxycytidine di- and triphosphate (dFdCDP, dFdCTP). dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis, dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. |
Purity | ≥ 98?% by HPLC |
Chemical Name | 2',2'-difluoro-2'-deoxycytidine; Gamcitabine; Gemcitera; Gemsar; Gemzar; LY-188011 |
Formula | C?H??F?N?O??HCl |
Permeability | Cell-permeable |
Molecular Weight | 299.66 g/mol |
CAS-No | 122111-03-9 |
Research Area | Kinases/Phosphatases |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from air and moisture |
Storage | -20 °C |
Expiry Date | 24 months |
Supplier Images |
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