產(chǎn)品詳情
簡單介紹:
NSC23766
詳情介紹:
Characteristics | Acell-permeable, reversible, and selective Rac1 inhibitor,inhibiting Rac1 activation by the Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam 1 (IC50 = 50 μM) without affecting the closely related GTPases, Cdc42, and RhoA activation. NSC 23766 has been used to investigate the role of Rac1 in such diverse cellular functions as stem cell mobilization, epithelial cell migration, angiogenesis, leukemia cell migration and growth, etc. |
Purity | ≥ 98?% by HPLC |
Chemical Name | N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine trihydrochloride |
Formula | C??H??N?.3HCl |
Permeability | Cell-permeable |
Molecular Weight | 530.97 g/mol |
CAS-No | 733767-34-5 |
Research Area | Kinases/Phosphatases |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from light and moisture |
Storage | -20 °C |
Expiry Date | 36 months |
Supplier Images |
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