產(chǎn)品詳情
簡(jiǎn)單介紹:
Necrostatin-5
詳情介紹:
Characteristics | Inhibits non-apoptotic cell deathpathway by inhibition of the death domain receptor-associated adaptor kinase RIP1. Three distinct mechanisms appear to be involved in necroptosis, the alternative active cell death pathway: T-loop dependent inhibition by necrostatin-1, partially T-loop independent inhibition by necrostatin-3 and indirect inhibition of RIP1 by necrostatin-5. |
Purity | ≥ 98?% by NMR |
Chemical Name | 3-p-Methoxyphenyl-5,6-tetramethylenothieno[2,3-d]pyrimidin-4-one-2-mercaptoethylcyanide; Nec-5 |
Formula | C??H??N?O?S? |
Permeability | Cell-permeable |
Molecular Weight | 383.49 g/mol |
CAS-No | 337349-54-9 |
Research Area | Kinases/Phosphatases |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from air and light |
Storage | -20 °C |
Expiry Date | 24 months |
Supplier Images |
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