產(chǎn)品詳情

  • 產(chǎn)品名稱：XAV939

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
XAV939
詳情介紹：
Characteristics A Tankyrase (TNKS) inhibitor (IC50 = 110 nM for TNKS1 and 4 nM for TNKS2). Antagonizes wnt signaling via stimulation of beta-catenin degradation and stabilization of axin. Inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1.
Purity ≥ 98?% by HPLC
Chemical Name 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thi opyrano[4,3-d]pyrimidin-4-one
Formula C??H??F?N?OS
Permeability Cell-permeable
Molecular Weight 312.31 g/mol
CAS-No 284028-89-3
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for XAV939 (ABIN412327) XAV939