產(chǎn)品詳情

  • 產(chǎn)品名稱：SB1518(Pacritinib)

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
SB1518(Pacritinib)
詳情介紹：
Purpose A potent JAK2/FLT3 inhibitor.
Characteristics Crystalline solid
Molecular formular: C28H32N4O3
Purity ≥ 98?% by HPLC
Chemical Name 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene
Formula C??H??N?O?
Permeability Cell-permeable
Molecular Weight 472.58 g/mol
CAS-No 937272-79-2
Comment

Synonyms:
11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene
A potent JAK2/FLT3 inhibitor. Displays equipotent activity against JAK2 (I = 23 nM) and FLT3 (IC = 22 nM). SB1518 displays potent anti-proliferative effects on myeloid and lymphoid cell lines driven by mutant or wild-type JAK2 or FLT3, resulting from cell cycle arrest and induction of apoptosis
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for SB1518 (Pacritinib) (ABIN1888946) SB1518 (Pacritinib)