產(chǎn)品詳情
簡單介紹:
HEK-293CellsIgG1IsotypeControl
詳情介紹:
Isotype | IgG1 |
Characteristics | This protein carries no "tag". The protein has a calculated MW of 26 kDa. The protein migrates as 35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Purity | >95?% as determined by SDS-PAGE. |
Sterility | 0.22 μm filtered |
Endotoxin Level | Less than 1.0 EU per μg by the LAL method. |
Background | Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases. |
Molecular Weight | 26 kDa |
UniProt | P01857 |
Research Area | Secondary Antibodies |
Application Notes | Optimal working dilution should be determined by the investigator. |
Restrictions | For Research Use only |
Format | Lyophilized |
Reconstitution | Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA. |
Buffer | 50 mM Tris, 100 mM Glycine,?pH 7.5 |
Handling Advice | Avoid repeated freeze-thaw cycles. |
Storage | -20 °C |
Storage Comment | Store at -20°C in lyophilized state after receipt. For long term storage, upon reconstitution rhIgG1 Fc should be aliquot and store at -20°C or -80°C. |
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